Jacksonville at St. Louis (-11.5, O/U 41.5)
No one wants a piece of Jacksonville these days. Oddsmakers have to inflate their lines until people do.
New Orleans at Chicago (-1, O/U 47.5)
How will Bears react to getting whipped by Lions last week? Saints will have short week to prepare for this one.
Philadelphia at NY Giants (-2.5, O/U 55.5)
Two struggling defences meet in this NFC East clash. At least the Eagles have scored some points lately.
Seattle at Indianapolis (+3, O/U 43)
Seahawks have pulled a Houdini act in both of their road victories so far. Will their luck finally catch up with them in Indy?
Baltimore at Miami (-3, O/U 43)
Ravens’ road struggles continued last week with loss at Buffalo. Surprising Dolphins coming off short week.
New England at Cincinnati (+3, O/U N/A)
Pats impressive in victory at Atlanta Sunday night. Bengals came back to earth against Cleveland after upsetting Green Bay.
Kansas City at Tennessee (spread N/A, O/U 41.5)
Oddsmakers holding off posting a line until confirming status of Titans QB Jake Locker. Both teams romped to victory last week.
Detroit at Green Bay (-7, O/U 52)
Packers coming off a bye. Green Bay needs victory to avoid falling three games behind Detroit in NFC North.
Carolina at Arizona (+1.5, O/U 42)
Panthers coming off a bye. Arizona rallied for victory last week at Tampa Bay, overcoming 10-0 deficit in fourth quarter.
San Diego at Oakland (+6, O/U 44)
Chargers held Cowboys scoreless in second half last week to win by nine. Raiders didn’t score in final three quarters of 24-14 loss to Washington.
Denver at Dallas (+6.5, O/U 55)
Oddsmakers struggling to make point spreads and totals that Broncos don’t cover or go over. Cowboys 2-2 after tough loss at San Diego.
Houston at San Francisco (-7, O/U 42.5)
How will Texans respond after blowing big lead last week to Seattle and losing in OT? San Fran got healthy last week with rout of Rams.
NY Jets at Atlanta (no lines)
Falcons have lost back-to-back games for first time in a long time under coach Mike Smith. Jets looked horrible in loss at Tennessee.